| | Seven Deadly Spins (Barcrest) (MPU5) | 1969 | Barcrest | m5seven | | 0.00 |
| | Seven's Above (Project) (PROCONN) | 1969 | Project | pr_sevab | | 0.00 |
| | Sevens & Melons (Project) (PROCONN) | 1969 | Project | pr_sevml | | 0.00 |
| | Sex Triv | 1985 | Status Games | sextriv | | 6.47 |
 | Sexual Trivia (Version 1.02SB, set 1) | 1985 | Kinky Kit and Game Co. | sextriv1 | Quiz / English *Mature* | 7.67 |
| Sexual Trivia (Version 1.02SB, set 2) (clone of: sextriv1) | 1985 | Kinky Kit and Game Co. | sextriv2 | Quiz / English *Mature* | 0.00 |
| | Sexy Boom | 1992 | Sang Ho Soft | sexyboom | | 4.67 |
| | Sexy Gal (Japan 850501 SXG 1-00) | 1985 | Nichibutsu | sexygal | | 0.00 |
 | Sexy Parodius (ver AAA) (clone of: sexyparo) | 1996 | Konami | sexyparoa | | 0.00 |
| Sexy Parodius (ver JAA) | 1996 | Konami | sexyparo | Shooter / Flying Horizontal *Mature* | 8.14 |
 | SF-X | 1983 | Nichibutsu | sfx | Shooter / Flying | 6.50 |
 | Shackled (US) | 1986 | Data East USA | shackled | Maze / Shooter Large | 7.80 |
 | Shadow Dancer (bootleg) (clone of: shdancer) | 1989 | bootleg | shdancbl | Platform / Fighter Scrolling | 0.00 |
| Shadow Dancer (Japan) (clone of: shdancer) | 1989 | Sega | shdancerj | | 0.00 |
| | Shadow Dancer (Mega-Tech) | 1990 | Sega | mt_shado | | 0.00 |
| Shadow Dancer (US) (clone of: shdancer) | 1989 | Sega | shdancer1 | | 0.00 |
| Shadow Dancer (World) | 1989 | Sega | shdancer | Platform / Fighter Scrolling | 7.77 |
| | Shadow Fighters | 1993 | Dutech Inc. | shadfgtr | | 0.00 |
 | Shadow Force (Japan Version 2) (clone of: shadfrce) | 1993 | Technos Japan | shadfrcejv2 | | 0.00 |
| Shadow Force (Japan Version 3) (clone of: shadfrce) | 1993 | Technos Japan | shadfrcej | | 0.00 |
